![]() These ratios vary across studies and across users but despite variance they all seem to be effective. Typically the ECA stack is consumed two or three times per day in a 1:10:10 or 1:10:15 ratio of ephedrine:caffeine:Aspirin. The effects of caffeine on dopamine levels are usually short lived, but ephedrine's partial action as a dopamine reuptake inhibitor lengthens the duration. Caffeine blocks adenosine receptors which lessens feelings of tiredness, and also increases dopamine levels, resulting in greater concentration, focus, and memory. It directly acts in the brain to increase the release of norepinephrine into the synaptic cleft, and also partially serves as a norepinephrine reuptake inhibitor, thereby also partially functioning as a dopamine reuptake inhibitor due to the shared action between the two terminals. Mechanisms of effect in energy gainĮphedrine acts to increase energy by its actions as a sympathomimetic amine. The final component in weight loss of the ECA stack is that of a simple stimulant the higher epinephrine and norepinephrine levels result in increased aerobic exercise performance and less fatigue. It is estimated that 60% – 75% of the weight loss from using the ECA stack comes from the anorectic effect, and the remainder from thermogenesis. However, these effects only last for about two weeks if the stack is not cycled, as the body becomes tolerant to ephedrine to some degree. It also binds with and competitively inhibits adenosine receptors in the brain, triggering the release of epinephrine and increasing cAMP levels further.Īspirin inhibits prostaglandin production outside of the cells, which, in conjunction with caffeine, greatly prolongs the thermogenic effects and increased metabolism by substaining elevated cAMP levels.Įphedrine also has an anorectic, or appetite-suppressing, effect. This is done via the production of phosphodiesterase inside the cells, and prostaglandins outside the cell, which both lower cAMP levels within the cell.Ĭaffeine inhibits the production of phosphodiesterase inside the cell and therefore slows cAMP breakdown. However, the body's negative feedback system then activates to normalize the metabolism. This causes a thermogenic effect, raising body temperature and increasing the user's metabolism in conjunction with the rest of the stack. Increased circulating norepinephrine in the body then acts on white adipose tissue by increasing cAMP levels. Ephedrine acts both as a beta agonist and stimulates the release of norepinephrine. ![]() NOTE: I didn't go to the doctor 'cause where I live they literally don't give a shit - I almost became a cripple as a teenager 'cause of a bad broken hand fix and it's a really common thing.The effects of the ECA stack in weight loss are primarily due to the ephedrine component. So, do I sacrifice possible efficiency and go for the main goal of losing weight as fast as possible, or do I wait it out for a month or two, build my stamina up, and then just absolutely go full ape mode for max efficiency? I tested one out and it helped me work for 2hrs, the 1st hour was hardcore, the 2nd one was working at a pace - I dig it. The plan is to take 25mg daily for three to four weeks, 5 days weekly. What my conundrum here is, do I seriously work on my conditioning for at least a month more and then do the ECA stack, or just start straight away with the stack and cut weight as fast as possible? I see the light and I'm gunning towards it. What I decided to do is to cut weight AFAP to at least 100-105kgs so I can continue working on my knee and reduce the stress on it 'cause I do not want to take my time with this and I do not want to feel this pain any longer. And my general mental health improved drastically. I lost a lot of fat but I keep gaining a lot of muscle (due to muscle memory I think), and I feel my knee getting stronger, because it hurts a lot less. I'm two months in now and somewhere between 110-115kg. After my totally random knee injury, which occurred while carrying heavy stuff, I've gained around 25/27kg (around 118.5kg total) in ~10 months.ĭuring that time I've also had Covid and went through a serious depression due to my grandparents passing, life in general, etc.Īfter seeing how much weight I've gained and how basic stuff started becoming a problem for me (like taking stairs to the 3rd floor), I've decided to go back to boxing even though my knee hurt like Hell. ![]()
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